Skip to content
Tessa Calhoun

Tessa Calhoun

Assistant Professor


The Calhoun lab probes dynamic interactions at biological membranes. In particular, we are focused on imaging the underlying mechanisms of drug-membrane interactions. Fungal and bacterial membranes are attractive drug targets as they provide a protective barrier between the cell and its environment and control the transport of ions and molecules into and out of the cell. The engineering of novel drugs is limited by an incomplete understanding of how these molecules react to different biological environments. To study these systems in vivo , we use advanced nonlinear optical microscopy techniques. 


Post-Doc, Lewis-Sigler Institute for Integrative Genomics, Princeton University
PhD, Chemistry from UC Berkeley
BS, Chemistry from Iowa State University


Chemical nature of ferroelastic twin domains in CH3NH3PbI3 perovskite 
Y. Liu, L. Collins, R. Proksch, S. Kim, B. R. Watson, B. Doughty, T. R. Calhoun, M. Ahmadi, A. V. Ievlev, S. Jesse, S. T. Retterer, A. Belianinov, K. Xiao, J. Huang, B. G. Sumpter, S. V. Kalinin, B. Hu, and O. S. Ovchinnikova 
Nat. Mater. (2018)

Flexible approach to vibrational sum-frequency generation using shaped near-infrared light 
A. U. Chowdhury, F. Liu, B. R. Watson, R. Ashkar, J. Katsaras, C. P. Collier, D. A. Lutterman, Y.-Z. Ma, T. R. Calhoun, and B. Doughty 
Opt. Lett. 43, 2038 (2018)

Compressed supercontinuum probe for transient absorption microscopy 
K. Higgins and T. R. Calhoun 
Opt. Lett. 43, 1750 (2018)

Elucidation of Perovskite Film Micro-Orientations using Two-Photon Total Internal Reflectance Fluorescence Microscopy
B. R. Watson, B. Yang, K. Xiao, Y.-Z. Ma, B. Doughty, and T. R. Calhoun 
J. Phys. Chem. Lett. 6, 3283 (2015)

Tessa Calhoun

Contact Information

The flagship campus of the University of Tennessee System and partner in the Tennessee Transfer Pathway.