Assistant Professor
Research
The Calhoun lab probes dynamic interactions at biological membranes. In particular, we are focused on imaging the underlying mechanisms of drug-membrane interactions. Fungal and bacterial membranes are attractive drug targets as they provide a protective barrier between the cell and its environment and control the transport of ions and molecules into and out of the cell. The engineering of novel drugs is limited by an incomplete understanding of how these molecules react to different biological environments. To study these systems in vivo , we use advanced nonlinear optical microscopy techniques.
Education
Post-Doc, Lewis-Sigler Institute for Integrative Genomics, Princeton University
PhD, Chemistry from UC Berkeley
BS, Chemistry from Iowa State University
Publications
Chemical nature of ferroelastic twin domains in CH3NH3PbI3 perovskite
Y. Liu, L. Collins, R. Proksch, S. Kim, B. R. Watson, B. Doughty, T. R. Calhoun, M. Ahmadi, A. V. Ievlev, S. Jesse, S. T. Retterer, A. Belianinov, K. Xiao, J. Huang, B. G. Sumpter, S. V. Kalinin, B. Hu, and O. S. Ovchinnikova
Nat. Mater. (2018)
Flexible approach to vibrational sum-frequency generation using shaped near-infrared light
A. U. Chowdhury, F. Liu, B. R. Watson, R. Ashkar, J. Katsaras, C. P. Collier, D. A. Lutterman, Y.-Z. Ma, T. R. Calhoun, and B. Doughty
Opt. Lett. 43, 2038 (2018)
Compressed supercontinuum probe for transient absorption microscopy
K. Higgins and T. R. Calhoun
Opt. Lett. 43, 1750 (2018)
Elucidation of Perovskite Film Micro-Orientations using Two-Photon Total Internal Reflectance Fluorescence Microscopy
B. R. Watson, B. Yang, K. Xiao, Y.-Z. Ma, B. Doughty, and T. R. Calhoun
J. Phys. Chem. Lett. 6, 3283 (2015)
Contact Information
- 209 Dabney-Buehler Hall
- 1420 Circle Dr.
- Knoxville, TN 37996-1600
- Phone: 865-974-3685
- E-mail: trcalhoun@utk.edu
- Group Website