• Request Info
  • Visit
  • Apply
  • Give
  • Request Info
  • Visit
  • Apply
  • Give

Search

  • A-Z Index
  • Map

Chemistry

  • About
    • Student Organizations
    • Connect With Us
    • Careers With Us
    • Employee/Student Travel Request
    • Share Your Dr. Schweitzer Story
  • Undergraduate Students
    • Majors and Minors
    • First Year Students
    • Undergraduate Research
    • Summer Programs
    • Chemistry Lab Excused Absence
    • Apply
  • Graduate Students
    • Our Programs
    • Graduate Student Resources
    • Research Open House
    • Apply
  • Faculty
  • People
  • Research
    • Research Areas
    • Facilities
  • News
Home » Thanh Do

Thanh Do

Thanh Do

January 23, 2024 by

ADDRESS
616 Dabney-Buehler Hall 1420 Circle Drive Knoxville, Tennessee 37996
Email
tdo5@utk.edu
Website
https://thanhdolab.com/
Phone
865-974-3260

Thanh Do

Assistant Professor

Education

Post-Doc, University of Illinois at Urbana-Champaign
PhD, Chemistry from UC Santa Barbara
BS, Chemistry and Mathematics from Gonzaga University

Research

My research combines ion-mobility mass spectrometry (IM-MS), mass spectrometry imaging (MSI), and computational modeling to bring a chemical physics outlook to problems of broad chemical interest. The overarching aims of my research are two-fold. The first is to develop fast and sensitive MS-based techniques and biophysical methods suitable for simultaneously assessing and predicting the structure, topology, composition and dynamics of exotic species in the gas phase. These species include small molecules, peptides and proteins in complex mixtures and volume-limited samples. The second overarching aim is to use these techniques for biological applications.

Awards

2023 Eli Lilly and Company Young Investigator Award
2022 ASMS Research Award

Selected Publications

Limbach, M. N.1; Antevksa, A.1; Oluwatoba, D. S.; Gray, A. L. H.; Carroll, X. B.; Hoffmann, C. M.; Wang, X.; Voehler, M. W.; Steren, C. A.; Do, T. D. Atomic View of Aqueous Cyclosporine A: Unpacking a Decades-Old Mystery. J. Am. Chem. Soc. 2022, 144, 12602-12607. PDF. CCDC 2149649–2149650

Gray, A. L. H.; Sawaya, M. R.; Acharyya, D.; Jinchao, L.; Edington, E.; Best, M. D.; Prosser, R. A.; Eisenberg, D. S.; Do, T. D. Atomic View of an Amyloid Dodecamer Exhibiting Selective Cellular Toxic Vulnerability in Acute Brain Slices. Protein Science 2022, 31 (3), 716-727. PDF, PDB ID: 7ROJ, 7ROL

Sade Yazdi, D.; Bar-Yosef, D. L.; Adsi, H.; Kreiser, T.; Sigal, S.; Bera, S.; Zaguri, D.; Shaham-Niv, S.; Oluwatoba, D. S.; Levy, D.; Gartner, M.; Do, T. D.; Frenkel, D.; Gazit, E. Homocysteine fibrillar assemblies display cross-talk with Alzheimer’s disease β-amyloid polypeptide. Proc. Natl. Acad. Sci. U.S.A. 2021, 118 (24), e2017575118.

Gray, A. L. H.1; Antevska, A.1; Link, B. A.; Bogin, B.; Burke, S.; Dupuy, S.; Collier, J. J.; Levine, Z.; Karlstad, M.; Do, T. D. α-CGRP Disrupts Amylin Fibrillization and Regulates Insulin Secretion: Implications on Diabetes and Migraine. Chem. Sci. 2021, 12, 5853-5864.

Neumann, E. K.; Do, T. D. ; Comi, T. J.; Sweedler, J. V. Exploring the Fundamental Structures of Life: Non-targeted, Chemical Analysis of Single Cells and Subcellular Structures. Angew. Chem. Int. Ed. 2019, 31, 9448 – 9465.

Chemistry

College of Arts & Sciences

552 Buehler Hall
1420 Circle Dr.
Knoxville, TN 37996-1600

Email: chemistry@utk.edu

Phone: 865-974-3141

 

The University of Tennessee, Knoxville
Knoxville, Tennessee 37996
865-974-1000

The flagship campus of the University of Tennessee System and partner in the Tennessee Transfer Pathway.

ADA Privacy Safety Title IX